CHIRAL TECHNOLOGIES EUROPE offers a FREE chiral method development service.

We will develop a chiral method for separation of racemic or isomeric mixtures suited to your analytical, semi-preparative or preparative applications.

Our team of chromatographers quickly screens all available DAICEL chiral HPLC columns with all possible mobile phase combinations: normal phase, polar organic mode and reverse phase, dependent upon your requirements.

We identify the best method to meet your project needs.

LCMS-compatible mobile phases are included in the column selection service if requested.

We will screen Daicel polysaccharide-derived (immobilised and coated), protein, anion exchange, zwitterionic and crown ether chiral phases until we find a suitable chiral method.

For semi-preparative HPLC applications, custom method development focuses on semi-preparative stationary phases to find the best column possible. Data obtained will accurately reflect projections of the preparative separations (milligrams to tens of grams) on 1-, 2-, and 5-cm I.D. columns.

Depending on your particular requirements, custom method development can also focus on loading and solubility studies for use in SFC and Simulated Moving Bed (SMB) systems.

The column selection service is performed under strict confidentiality with a Confidential Disclosure Agreement (CDA) being executed, when necessary, prior to the commencement of the project.

In addition, you can utilise our separation services, carried out by the team of chemists and engineers, which allows you to benefit from the combination of our technical expertise and well-known DAICEL technology

For more information contact us at

Method Development Strategies

Chiral Technologies has recently developed comprehensive Screening Strategies — covering both immobilized and coated CSPs, and protein-based stationary phases for those customers who prefer to carry out custom method development in-house. The Screening Strategies guide you in a decision making process to select the most appropriate combination of CSP, mobile phase, and chromatography mode, that will be effective in separating your compound.

Chiral Technologies CTE scientific method word cloud

To learn more about our method development, click on one of the screening strategy guides below.







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